In the Vatican Infirmary, after suffering what should have been a fatal stroke, the Pontiff suddenly awakens from his comatose, brain-dead state and orders that he be kept alive on machines indefinitely, that God is now speaking through him. He then begins issuing mandates that will change the course and ultimately the very nature of the worldwide Roman Catholic Church.
At the same time, a half a world away in San Francisco, a young career woman begins to be haunted by demons, her condition escalating rapidly. She seeks the aid of a priest, who - along with her fiance - is forced to try more and more desperate measures to release her from this diabolic possession.
These two men are, unbeknownst to them, the ones preordained by God to see through the deception at the Vatican and stop Satan's plot, but will they be distracted by their efforts to save the woman until it is too late to save the world?
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